Thrombotic Risk DNA Test
Determine your genetic risk of developing blood clots and thrombosis.
Measures:
- Variant in F5, F2 and MTHFR genes
Collection methods:
Buccal swabs
$195.00
- Discreet shipping
- Accredited lab
- Secure Online Results
- Highest accuracy
- Discreet
- Results in 1-3 business days
About the test
Understand Your Genetic Risk for Blood Clots
Thrombosis occurs when a blood clot forms inside a blood vessel, restricting blood flow. One of the most common forms is deep vein thrombosis (DVT), which typically develops in the legs. Symptoms of DVT include pain, swelling, redness, and warmth in the affected area. If left untreated, a clot can break loose and travel to the lungs, leading to a life-threatening condition known as pulmonary embolism (PE).
Certain genetic factors can increase your risk of developing blood clots. Variants in genes such as F5 (Factor V Leiden) and F2 (Prothrombin) can make your blood more prone to clotting. Identifying these genetic risks can help you take preventive measures, such as lifestyle changes or medical interventions, to reduce the likelihood of serious complications.
A simple DNA test can reveal whether you carry these genetic variants, empowering you with the knowledge to protect your vascular health.
Genetic Profile
Genetic Factors in Thrombosis Risk
Genetic changes in three key genes are analyzed in this thrombotic risk test. Each of these variations contributes to an increased risk of developing blood clots, which can lead to serious conditions such as deep vein thrombosis (DVT) or pulmonary embolism (PE). Understanding your genetic predisposition can help you take proactive steps toward prevention and better cardiovascular health.
If you suspect deep vein thrombosis (DVT), seek medical attention immediately, as a clot can break loose and travel to critical areas of the body.
A clot that reaches the lungs can cause a pulmonary embolism (PE), a life-threatening condition that blocks essential blood flow. Symptoms include sudden shortness of breath, chest pain, coughing up blood-streaked mucus, and a rapid heartbeat.
If a clot travels to the brain, it may lead to cerebral venous thrombosis, which can result in impaired speech, difficulty moving, vision problems, and severe headaches.
Every year, more people die from blood clots than breast cancer and HIV combined. A simple DNA test can help uncover your genetic risk and empower you to take preventive action.
- Maintain a healthy weight
- Follow a nutritious diet
- Increase circulation through regular exercise
- Avoid sitting or standing still for long periods
- Quit smoking
- Lower homocysteine levels by consuming enough folate and other B vitamins
- Wear compression stockings on long flights
- If your risk is very high, consult a doctor for treatments like anticoagulants
- F5 – Factor V Leiden mutation (1691G>A)
- F2 – Prothrombin mutation (20210G>A)
- MTHFR – Two mutations (677C>T and 1298A>C)
We inherit two copies of each gene—one from each parent. These genetic mutations may vary: you can inherit two normal copies (homozygous normal), two mutated copies (homozygous mutant), or one normal and one mutated copy (heterozygous). These combinations influence your risk for thrombosis,
These combinations influence your risk for thrombosis, with the following possible outcomes:
- Factor V Leiden mutation (heterozygous 1691G>A): 3X to 8X increased risk of thrombosis and 2X to 11X increased risk of miscarriage
- Factor V Leiden mutation (homozygous 1691G>A): 10X to 80X increased risk of thrombosis and 2X to 11X increased risk of miscarriage
- Prothrombin mutation (heterozygous 20210G>A): 2X to 5X increased risk of thrombosis and 2X to 3X increased risk of miscarriage
- Prothrombin mutation (homozygous 20210G>A): >5X increased risk of thrombosis and 2X to 3X increased risk of miscarriage
- MTHFR mutation (homozygous 677C>T): Increased risk of thrombosis if folate levels are low
- Two MTHFR mutations (677C>T and 1298A>C): Increased risk of thrombosis if folate levels are low
The Hidden Dangers of Blood Clots
If you suspect deep vein thrombosis (DVT), seek medical attention immediately, as a clot can break loose and travel to critical areas of the body.
A clot that reaches the lungs can cause a pulmonary embolism (PE), a life-threatening condition that blocks essential blood flow. Symptoms include sudden shortness of breath, chest pain, coughing up blood-streaked mucus, and a rapid heartbeat.
If a clot travels to the brain, it may lead to cerebral venous thrombosis, which can result in impaired speech, difficulty moving, vision problems, and severe headaches.
Every year, more people die from blood clots than breast cancer and HIV combined. A simple DNA test can help uncover your genetic risk and empower you to take preventive action.
Reducing Your Risk of Blood Clots
- Maintain a healthy weight
- Follow a nutritious diet
- Increase circulation through regular exercise
- Avoid sitting or standing still for long periods
- Quit smoking
- Lower homocysteine levels by consuming enough folate and other B vitamins
- Wear compression stockings on long flights
- If your risk is very high, consult a doctor for treatments like anticoagulants
Variants Tested
- F5 – Factor V Leiden mutation (1691G>A)
- F2 – Prothrombin mutation (20210G>A)
- MTHFR – Two mutations (677C>T and 1298A>C)
We inherit two copies of each gene—one from each parent. These genetic mutations may vary: you can inherit two normal copies (homozygous normal), two mutated copies (homozygous mutant), or one normal and one mutated copy (heterozygous). These combinations influence your risk for thrombosis,
Patient Genotype and Thrombotic Risk
These combinations influence your risk for thrombosis, with the following possible outcomes:
- Factor V Leiden mutation (heterozygous 1691G>A): 3X to 8X increased risk of thrombosis and 2X to 11X increased risk of miscarriage
- Factor V Leiden mutation (homozygous 1691G>A): 10X to 80X increased risk of thrombosis and 2X to 11X increased risk of miscarriage
- Prothrombin mutation (heterozygous 20210G>A): 2X to 5X increased risk of thrombosis and 2X to 3X increased risk of miscarriage
- Prothrombin mutation (homozygous 20210G>A): >5X increased risk of thrombosis and 2X to 3X increased risk of miscarriage
- MTHFR mutation (homozygous 677C>T): Increased risk of thrombosis if folate levels are low
- Two MTHFR mutations (677C>T and 1298A>C): Increased risk of thrombosis if folate levels are low
How it works
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Genetic Factors in Thrombosis Risk
Genetic changes in three key genes are analyzed in this thrombotic risk test. Each of these variations contributes to an increased risk of developing blood clots, which can lead to serious conditions such as deep vein thrombosis (DVT) or pulmonary embolism (PE). Understanding your genetic predisposition can help you take proactive steps toward prevention and better cardiovascular health.
