




Osteoporosis Risk DNA Test
Discover your genetic risk for blood clotting and thrombotic conditions.

Measures:
- Genetic variants that affect bone density and strength
- Inheriting certain variants may increase the risk of osteoporosis
- Take proactive steps to support and improve your bone health
Collection methods:

Buccal swabs
$195.00
- Discreet shipping
- Accredited lab
- Secure Online Results
- Highest accuracy
- Discreet
- Results in 1-3 business days
About the test
Genetic Risk Assessment for Osteoporosis and Osteoarthritis
Osteoporosis is a condition that causes bones to become weak and brittle, increasing the risk of fractures, even from minor falls or injuries. This condition is particularly common in older adults and becomes more prevalent with age. In fact, osteoporosis-related fractures are more common than heart attacks, strokes, and breast cancer combined.
In addition to osteoporosis, osteoarthritis is another joint-related disease characterized by the breakdown of cartilage in the joints, leading to pain, swelling, and reduced movement. It commonly affects the hands, knees, hips, and lower back.
By taking this test, you can find out whether you carry genetic variants that could increase your risk for osteoporosis and osteoarthritis, allowing you to take proactive steps in maintaining your bone and joint health.

Genetic Profile
Proactive Bone Health Management
Understanding your genetic susceptibility to osteoporosis allows you to take early steps in delaying bone health issues and minimizing the impact of bone loss.
- CYP2R1 – Increases the risk of vitamin D deficiency, which affects calcium absorption, essential for maintaining healthy bones.
- GC – Increases the risk of vitamin D deficiency, impacting calcium absorption and bone health.
- WNT16 – Heightens the risk of reduced bone formation, affecting bone density.
- GDF5 – Influences the regulation of bone, joint, and cartilage development, maintenance, and repair.
- COL1A1 – Impacts collagen formation, a key component for bone strength and structure.
Strong, healthy bones are essential for supporting our structure, anchoring muscles and ligaments, protecting internal organs, and storing important minerals.
From birth until around age 30, bone production outpaces bone breakdown, reaching peak bone mass by age 30. After this, bone remodeling continues, but the rate of bone breakdown gradually surpasses bone production, leading to a slow decrease in bone mass. Factors like poor bone growth in childhood and accelerated bone loss in adulthood can increase the risk of osteoporosis.
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Calcium-Rich Diet: Ensure adequate intake of calcium, which is essential for bone health. Foods like dairy products, leafy greens, and fortified foods are excellent sources.
-
Vitamin D: Vitamin D helps the body absorb calcium. Sun exposure, fortified foods, and supplements can help maintain healthy vitamin D levels.
-
Regular Exercise: Weight-bearing exercises like walking, jogging, and strength training help strengthen bones and improve bone density.
-
Avoid Smoking: Smoking can weaken bones, leading to an increased risk of osteoporosis.
-
Limit Alcohol Consumption: Excessive alcohol intake can interfere with bone remodeling and increase the risk of bone loss.
-
Maintain a Healthy Weight: Being underweight can increase bone loss, while being overweight can add stress on the bones, increasing fracture risk.
-
Hormonal Balance: For women, maintaining healthy estrogen levels, especially after menopause, can help protect bones.
-
Bone-Healthy Medications: In some cases, medications like bisphosphonates or hormone therapy may be recommended to strengthen bones.
-
Avoid Falls: Take steps to prevent falls by improving balance, using assistive devices when necessary, and making home safety adjustments.
-
Healthy Lifestyle: Eating a balanced diet with adequate protein, avoiding high-sodium foods, and getting enough sleep contribute to overall bone health.
Variants Tested
- CYP2R1 – Increases the risk of vitamin D deficiency, which affects calcium absorption, essential for maintaining healthy bones.
- GC – Increases the risk of vitamin D deficiency, impacting calcium absorption and bone health.
- WNT16 – Heightens the risk of reduced bone formation, affecting bone density.
- GDF5 – Influences the regulation of bone, joint, and cartilage development, maintenance, and repair.
- COL1A1 – Impacts collagen formation, a key component for bone strength and structure.
Decreasing Bone Mass with Age in Men & Women
Strong, healthy bones are essential for supporting our structure, anchoring muscles and ligaments, protecting internal organs, and storing important minerals.
From birth until around age 30, bone production outpaces bone breakdown, reaching peak bone mass by age 30. After this, bone remodeling continues, but the rate of bone breakdown gradually surpasses bone production, leading to a slow decrease in bone mass. Factors like poor bone growth in childhood and accelerated bone loss in adulthood can increase the risk of osteoporosis.
Tips for Preventing Osteoporosis
-
Calcium-Rich Diet: Ensure adequate intake of calcium, which is essential for bone health. Foods like dairy products, leafy greens, and fortified foods are excellent sources.
-
Vitamin D: Vitamin D helps the body absorb calcium. Sun exposure, fortified foods, and supplements can help maintain healthy vitamin D levels.
-
Regular Exercise: Weight-bearing exercises like walking, jogging, and strength training help strengthen bones and improve bone density.
-
Avoid Smoking: Smoking can weaken bones, leading to an increased risk of osteoporosis.
-
Limit Alcohol Consumption: Excessive alcohol intake can interfere with bone remodeling and increase the risk of bone loss.
-
Maintain a Healthy Weight: Being underweight can increase bone loss, while being overweight can add stress on the bones, increasing fracture risk.
-
Hormonal Balance: For women, maintaining healthy estrogen levels, especially after menopause, can help protect bones.
-
Bone-Healthy Medications: In some cases, medications like bisphosphonates or hormone therapy may be recommended to strengthen bones.
-
Avoid Falls: Take steps to prevent falls by improving balance, using assistive devices when necessary, and making home safety adjustments.
-
Healthy Lifestyle: Eating a balanced diet with adequate protein, avoiding high-sodium foods, and getting enough sleep contribute to overall bone health.
How it works


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Proactive Bone Health Management
Understanding your genetic susceptibility to osteoporosis allows you to take early steps in delaying bone health issues and minimizing the impact of bone loss.